FDA Drugs MCP Server

A Model Context Protocol (MCP) server for accessing FDA drug data through the OpenFDA API.

Features

• Drug Name Search: Search for drugs by brand or generic name
• Indication Search: Find drugs by medical condition or therapeutic indication
• Detailed Drug Information: Get comprehensive drug details including clinical data
• Similar Drug Discovery: Find drugs with similar mechanisms of action or indications
• Application History: Access FDA application and approval history
• BLA/NDA Focus: Defaults to approved drugs (BLA/NDA), excludes generics (ANDA) unless specified

Available Tools

1. search_drug_by_name - Search for drugs by brand or generic name
2. search_drug_by_indication - Search for drugs by medical indication
3. get_drug_details - Get comprehensive details for a specific drug
4. search_similar_drugs - Find drugs similar to a reference drug
5. get_drug_application_history - Get FDA application history

Run Locally

• HTTP (recommended):

  bash

  pip install -r requirements.txt
  PORT=8081 TRANSPORT=http python server.py
  

• STDIO (backwards compatible):

  bash

  pip install -r requirements.txt
  python server.py
  

Use With Clients

Smithery (Custom Container)

• This repo includes Dockerfile and smithery.yaml configured for HTTP streamable transport.
• Deploy via https://smithery.ai/new by connecting your GitHub repo.
• Local test (HTTP):
  bash

  docker build -t fda-drugs-mcp .
  docker run -p 8081:8081 -e PORT=8081 fda-drugs-mcp
  npx @smithery/cli playground --port 8081
  

Installing via Smithery

To install FDA Drugs MCP Server automatically via Smithery:

npx -y @smithery/cli install @plainyogurt21/fda-drugs-mcp

Config fields supported when launching via Smithery:

• fdaApiKey: OpenFDA API key
• logLevel: DEBUG | INFO | WARNING | ERROR | CRITICAL

Cline (CLI MCP Client)

• Cline supports MCP over HTTP. Start the server:
  bash

  PORT=8081 TRANSPORT=http python server.py
  

• Then configure Cline to connect to http://localhost:8081 as an MCP server. If Cline supports session config, pass fdaApiKey in the session config.

Claude Code

• Claude Code supports both STDIO and HTTP MCP servers.
• Recommended: run HTTP and add a server entry pointing to http://localhost:8081.
• Alternative (STDIO): point Claude Code to run python server.py in this folder.

Other MCP Clients

• Any MCP client that supports streamable HTTP can connect to http://<host>:8081.
• Per-request config can be passed using Smithery’s config query parameter format.

Notes

• HTTP mode uses CORS with permissive defaults to work across clients.
• The server reads the OpenFDA API key from, in order of precedence:
  • Per-request config fdaApiKey
  • STDIO/runtime config or env FDA_API_KEY
  • Built-in default (see utils/config.py)

Testing (local modules)

python test_server.py